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Clonazepam is a prescription benzodiazepine medication used to treat seizure disorders, panic disorder, and certain types of anxiety. It works by enhancing the activity of GABA, a calming neurotransmitter in the brain, which helps reduce excessive nerve activity. Because of its longer duration of action compared to some other benzodiazepines, clonazepam is often used for conditions requiring more sustained symptom control.

Dosage of clonazepam varies based on the condition being treated, age, and individual response. For panic disorder, the usual starting dose is 0.25 mg twice daily, which may be increased gradually to a typical maintenance dose of 0.5–1 mg per day. For seizure disorders, initial doses often start at 0.5 mg three times daily, with slow increases as needed; maximum daily doses may reach 20 mg in divided doses for certain seizure conditions. Clonazepam should be taken exactly as prescribed, and dose adjustments must be made cautiously.

There are significant warnings associated with clonazepam use. Long-term or high-dose use can lead to physical dependence, tolerance, and addiction. Abrupt discontinuation may cause serious withdrawal symptoms, including seizures, severe anxiety, tremors, and insomnia; therefore, the medication should be tapered gradually under medical supervision. Combining clonazepam with opioids, alcohol, or other central nervous system depressants can result in dangerous sedation, respiratory depression, or even death.

Common side effects of clonazepam include drowsiness, dizziness, fatigue, impaired coordination, and memory difficulties. Some individuals may experience depression, mood changes, or confusion, especially at higher doses or in older adults. Serious side effects can include difficulty breathing, severe weakness, or unusual behavior changes. Patients should avoid driving or operating heavy machinery until they understand how clonazepam affects them and should seek immediate medical attention if severe or unexpected symptoms occur.