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Oxycodone is a prescription opioid pain medication used to manage moderate to severe pain when other pain treatments are not effective. It works by binding to opioid receptors in the brain and spinal cord, which reduces the perception of pain. Oxycodone is commonly prescribed after surgery, for injury-related pain, or for certain chronic pain conditions. Because it is a Schedule II controlled substance, it has a high potential for misuse, dependence, and addiction.

Dosage of oxycodone depends on the patient’s pain level, opioid tolerance, age, and overall health. For immediate-release formulations, typical starting doses for adults range from 5–15 mg every 4–6 hours as needed for pain. Extended-release (ER) forms are usually prescribed at 10 mg every 12 hours, with careful dose adjustments over time. Oxycodone should be taken exactly as prescribed, and tablets should not be crushed, chewed, or broken, especially extended-release versions, as this can cause a dangerous overdose.

There are serious warnings associated with oxycodone use. It can cause respiratory depression, which means slowed or stopped breathing, particularly at higher doses or when combined with alcohol, benzodiazepines, or other sedatives. Long-term use can lead to physical dependence, and sudden discontinuation may result in withdrawal symptoms such as restlessness, muscle pain, sweating, and nausea. Oxycodone should be used with caution in individuals with lung disease, liver or kidney problems, or a history of substance use disorder.

Common side effects of oxycodone include drowsiness, constipation, nausea, vomiting, dizziness, and itching. More serious side effects may include confusion, low blood pressure, slow breathing, or loss of consciousness. To reduce risks, patients are often advised to use stool softeners, avoid driving until they know how the medication affects them, and maintain regular follow-ups with their healthcare provider. Immediate medical attention is required if signs of overdose occur, such as extreme sleepiness, blue lips, or difficulty breathing.