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Codeine is a prescription opioid medication commonly used to treat mild to moderate pain and, in some formulations, to suppress cough. It works by binding to opioid receptors in the brain and spinal cord, altering how the body perceives pain and reducing the urge to cough. Codeine is often combined with other medications such as acetaminophen or guaifenesin to enhance its therapeutic effects. Due to its sedative and habit-forming properties, Codeine is classified as a controlled substance and should be used only under medical supervision.

The typical dosage of Codeine depends on the condition being treated. For pain, adults are commonly prescribed 15 mg to 60 mg every 4 to 6 hours as needed, not exceeding the maximum daily dose recommended by a healthcare provider. For cough, lower doses such as 10 mg to 20 mg every 4 to 6 hours may be used. Dosage adjustments are often required for elderly patients, those with kidney or liver disease, and Codeine is not recommended for children due to the risk of serious breathing problems.

There are several important warnings associated with Codeine use. It can cause respiratory depression, especially at higher doses or when combined with alcohol, benzodiazepines, or other central nervous system depressants. Individuals with asthma, sleep apnea, or a history of substance abuse should use Codeine with extreme caution or avoid it altogether. Codeine should not be used during pregnancy unless clearly necessary, as it may cause withdrawal symptoms in newborns. Prolonged use can lead to dependence and addiction.

Common side effects of Codeine include drowsiness, dizziness, constipation, nausea, and vomiting. Some patients may also experience itching, dry mouth, or sweating. Serious side effects such as slow or shallow breathing, severe confusion, fainting, or allergic reactions require immediate medical attention. Long-term use may worsen constipation and increase the risk of tolerance, requiring higher doses for the same effect.

Codeine can be an effective medication for pain relief and cough suppression when used appropriately. Adhering to the prescribed dosage, understanding the warnings, and monitoring for side effects are essential to ensure safe use. Patients should follow their healthcare provider’s instructions closely and avoid combining Codeine with other substances that increase the risk of serious complications.